Those who are on diclofenac need to read this

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Selective COX-2 Inhibitors Cause Less GI Irritation Than NSAID Plus PPI

Alice Goodman

June 18, 2010 (Rome, Italy) ? Patients with rheumatoid arthritis and
osteoarthritis treated with a selective cyclooxygenase-2 inhibitor for
inflammation and pain were 4 to 5 times less likely to develop
clinically significant upper and lower gastrointestinal problems than
those who were treated with diclofenac, a nonselective nonsteroidal
anti-inflammatory drug, plus a proton pump inhibitor, according to
results of the Celecoxib vs Omeprazole and Diclofenac in Patients With
Osteoarthritis and Rheumatoid Arthritis (CONDOR) study. The study was
published online June 17 in The Lancet to coincide with its
presentation here at the European League Against Rheumatism (EULAR)
Congress 2010.

Lead author of the study, Francis K.I. Chan, MD, from the Department
of Medicine and Therapeutics, Prince of Wales Hospital, at the Chinese
University of Hong Kong, called these findings relevant for patients
who require long-term anti-inflammatory therapy and who are at
increased gastrointestinal risk but not increased cardiovascular risk
.

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Read the full article here:

http://www.medscape.com/viewarticle/723793

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