…successfully reversed the SHR animals' symptoms of high blood
pressure, a pre-diabetes condition called insulin resistance, and
immune suppression. …
…The team went on to test whether administration of a protease-
blocking drug could reverse the multiple metabolic complications in
the rat strain. They administered doxycycline, a seemingly unlikely
candidate to have such a beneficial effect. Infectious disease
specialists often prescribe doxycycline, an antibiotic, to counter
bacterial infections. However, in laboratory tests doxycycline also
blocks the activity of certain proteases in the SHR strain of rat.
The researchers found that protein receptors on the surface of SHR
cells become clipped off as the animals develop hypertension. They
used a novel visualization technique to show that after several weeks
of ingesting doxycycline in their drinking water, the SHR rats
developed cells that again bristled with normal CD18 and insulin
receptors. The animals' metabolic conditions simultaneously improved;
blood pressure normalized and symptoms of immune suppression
disappeared. …
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MYCOPLASMA REGISTRY REPORTS
for gulf war syndrome & chronic fatigue syndrome