The following case study is reflective of a number of localized scleroderma anecdotal reports received by Road Back Foundation from parents of children with pediatric linear scleroderma (En Coup de Sabre) responding successfully to long-term treatment with oral penicillin.
Effect of penicillin G on corium thickness in linear morphea of childhood: An analysis using ultrasound technique. Pediatr Dermatol. 1999 Jul-Aug;16(4):314-6.
Case report of a child with a 6-year history of linear morphea, responding positively to treatment with intravenous penicillin G (5 MU aqueous, 3 times per day) for 10 days, consecutively, and ultrasound confirmation of reduced thickness of corium.