NIH RESEARCH PROJECT CANDIDA AND RA

[Nason]

I HAVE BEEN USING MINOCIN FOR RA SINCE 2004. I JUST CAME FROM A VISIT WITH A LOCAL DOCTOR WHO IS AN IMMUNE AND ALLERGY SPECIALIST. WENT FOR A DIFFERENT REASON THAN MY RA. IN THE COURSE OF THE VISIT WHEN I TOLD HIM I HAD RA HE TOLD ME ABOUT A RESEARCH PROJECT DONE BY THE NIH (NATIONAL INSTITUTE OF HEALTH) THAT IS JUST ABOUT COMPLETED AND HE EXPECTS THAT THEY WILL RELEASE THEIR RESULTS SOON. APPARENTLY THEY ARE STUDYING THE ROLE OF GASTROINTESTINAL MICROBES IN RA. THE RESULTS COULD TRANSFORM OUR UNDERSTANDING OF THE RELATIONSHIP BETWEEN MICROBES AND HUMANS AND LEAD TO INNOVATIVE DIAGNOSTIC TESTS AND FUTURE TREATMENTS FOR RA. MY DOCTOR INDICATED THAT THEY BELIEVE THERE IS A VERY STRONG RELATION BETWEEN CANDIDA AND RA. THE TESTS THEY PERFORMED ON MICE WORKED. THEY KILLED THE YEAST AND THE RA WAS GONE. THIS RESEARCH IS BEING DONE AT NEW YORK UNIVERSITY SCHOOL OF MEDICINE. I HAVE THE DOCTOR’S NAME. HAS ANYONE HEARD OF THIS? OR HAVE MORE INFORMATION? MY DOCTOR TOLD ME TO KEEP IN TOUCH WITH HIM AND AS SOON AS HE HEARS MORE NEWS HE WILL PASS IT ON. HE GUESSES THAT IT WILL BE MADE PUBLIC IN ABOUT ONE YEAR. MY QUESTION IS: ANYONE ABLE TO GET MORE INFO SOONER? THERE MUST BE A WAY TO CONTACT THEM DIRECTLY AND FIND OUT WHAT IT IS ALL ABOUT. I KNOW I HAVE A CANDIDA PROBLEM. DOES EVERYONE WITH RA HAVE THIS PROBLEM? IF YOU GOOGLE “NIH” AND “GUT BIOME” OR “CANDIDA ARTHRITICA” RHEUMATOID MOUSE MODEL, IT WILL GIVE MORE INFORMATION. THANKS BETTE (NASON)

[Maz]

@Nason wrote:

IN THE COURSE OF THE VISIT WHEN I TOLD HIM I HAD RA HE TOLD ME ABOUT A RESEARCH PROJECT DONE BY THE NIH (NATIONAL INSTITUTE OF HEALTH) THAT IS JUST ABOUT COMPLETED AND HE EXPECTS THAT THEY WILL RELEASE THEIR RESULTS SOON. APPARENTLY THEY ARE STUDYING THE ROLE OF GASTROINTESTINAL MICROBES IN RA. THE RESULTS COULD TRANSFORM OUR UNDERSTANDING OF THE RELATIONSHIP BETWEEN MICROBES AND HUMANS AND LEAD TO INNOVATIVE DIAGNOSTIC TESTS AND FUTURE TREATMENTS FOR RA. MY DOCTOR INDICATED THAT THEY BELIEVE THERE IS A VERY STRONG RELATION BETWEEN CANDIDA AND RA. THE TESTS THEY PERFORMED ON MICE WORKED. THEY KILLED THE YEAST AND THE RA WAS GONE. THIS RESEARCH IS BEING DONE AT NEW YORK UNIVERSITY SCHOOL OF MEDICINE. I HAVE THE DOCTOR’S NAME. HAS ANYONE HEARD OF THIS? OR HAVE MORE INFORMATION?

Nason, thanks so much for sharing this info! When you have the research info, would be grateful if you could post links here. I ran some searches on the key words you provided, but had no luck other than pulling up some other research on PubMed. Here are a couple that came up, but there are more:

http://www.ncbi.nlm.nih.gov/pubmed/21802979

http://www.ncbi.nlm.nih.gov/pubmed/20807027

Recently, I was introduced by my LLMD and Nancy (one of our RBF forum volunteers), to an organism being studied by an AP doc in AZ, called Protomyxozoa rheumatica. I think when you listen to his audio interview on Talk Radio (link pasted below), you’ll find what he has to say about candida and bio-films to be of some interest. I have been tested for this organism by this doc’s labs and received a picture of the bio-film in my blood with P. rheumatica holed up in the bio-film. In a nutshell, what this doc is suggesting from his research is that this protozoan may be the “premier pathogen” in RA and other inflammatory rheumatic and neuro AI diseases. It is a bio-film loving organism that is susceptible to tetras and plaquenil (interesting!) and other anti-microbials that treat malaria-like protozoan piroplasms. Once the organism is released from its bio-film, other opportunistic bugs and fungus are released from the bio-film and much easier to treat. This would tie nicely with your doc’s suspicions. Also, while talking with my doc about this, I asked if this could be the reason why so many rheumatics on AP find they struggle with overt candida infections soon after beginning treatment and he said he felt this was probably true. Candida is a naturally occurring flora in the gut that loves bio-film (like the slimey matrix found on stagnant ponds and lines the gut from mouth to anus). We are apt to blame abx for causing these overt candida infections as this is what we’re told in the conventional literature on the subject. However, what if anti-microbial therapy is disturbing bio-film communities and, once the targeted pathogens are being released from their hidey-holes from these disturbed bio-films, candida is also released? It would make sense, then, to not only treat rheumatic disease with a tetra or other abx, but to also target candida as it is being released. In other words, it’s not the abx that are the problem, but the bio-film loving organisms that trap candida in their matrix.

New rationales like this are becoming available for study now as researchers get more closely entwined in looking at microbial causes for RA. Candida is certainly inflammatory when its levels in the gut go into unhealthy ranges, but candida, itself, may not be the “premier pathogen,” as such, but just an opportunistic one that is better treated when the bio-films are being dismantled and properly treated. This research is still in its infancy, but worth listening to, if interested in this topic and perhaps also worth sharing with your doc? Just click on “here” button to listen to radio interview…Dr. F. speaks about 10 mins into the show. You can skip the callers at the end. 😉

http://www.betterhealthguy.com/joomla/blog/243-dr-stephen-fry-on-fl1953

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