Home Forums General Discussion Lyme vaccine

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  • #460344
    richie
    Participant

    The FDA has fast tracked a lyme vaccine -which is causing quite a stir in the US –Co. is Valneva =-a French co.
    mOre details are all over google or Newsday.com

    #460345
    Maz
    Keymaster

    Hi Richie,

    This is the reinvention of the OSPA vaccine (originally called Lymerix) that was withdrawn from the US market.

    New Lyme Vaccine

    New company, new Euro clinical trials, yet using the same old formula that did not succeed in the US market and which it was claimed was causing RA in certain genetic haplotypes (HLA-DRB1*0401) – the same haplotype associated with RA, MS and chronic Lyme disease.

    The story is documented here: The Lyme vaccine: a cautionary tale

    The relationship of OSPA and chronic Lyme arthritis was written about by Dr. Steere, the rheumatologist who is credited with the discovery of Lyme in CT, causing a very large cluster of JRA, yet he denies any correlation with the OSPA vaccine causing chronic arthritis in mouse models, which isn’t wholly convincing without replicated human trials.

    Relationship between Immunity to Borrelia burgdorferi Outer-surface Protein A (OspA) and Lyme Arthritis

    Moral of the story, if considering this new vaccine, get informed and get genetic haplotype testing in advance, something the study authors above state was considered too expensive and one of the reasons for the vaccine’s failure. Also note that the OSPA protein of the Lyme bug that was used in the old vaccine was specific to the most prevalent strain that is found in the US, so I don’t understand why this new (old) vaccine is being tested in Europe in human clinical trials where other borrelial strains are more prevalent and when it could potentially be marketed again in the US.

    Severe, swift onset RA as a result of Lyme disease
    Current Meds: Biaxin (500mg BID), Tetracycline (500mg BID), Tirosint (88mcg), Liothyronine (10 mcg), Compounded Liposomal Artemisinin, LDN (3mg), Topical Progesterone,
    Current Supps: Curcumin, Bovine Colostrum, ALA. NAC, Milk Thistle, Super Liquid Folate/B12/B-Complex, Probiotics, Vit D3
    Supportive Measures: IV Myer's Cocktails, IV Glutathione, FIR Sauna, Gluten-free diet, Gym.

    #460346
    richie
    Participant

    Its also has a phase 1 in the USA—-I happened to see where a vaccine was discontinued in I think 2006 because of lack of interest and lack of sales

    #460347
    Maz
    Keymaster

    This is one to observe over the next few years, Richie. Thanks for sharing.

    Severe, swift onset RA as a result of Lyme disease
    Current Meds: Biaxin (500mg BID), Tetracycline (500mg BID), Tirosint (88mcg), Liothyronine (10 mcg), Compounded Liposomal Artemisinin, LDN (3mg), Topical Progesterone,
    Current Supps: Curcumin, Bovine Colostrum, ALA. NAC, Milk Thistle, Super Liquid Folate/B12/B-Complex, Probiotics, Vit D3
    Supportive Measures: IV Myer's Cocktails, IV Glutathione, FIR Sauna, Gluten-free diet, Gym.

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