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Flagyl (Metronidazole)

Flagyl is in the nitroimidazole class of antibiotics and has been used successfully to treat cases of intestinal pseudo-obstruction, a potential complication in patients with systemic scleroderma who may develop slowed gut motility that can lead to intestinal overgrowths of various microbes, fungi and parasites.

Nihon Rinsh ō Menʾeki Gakkai. 2011;34(1):53-61.

Case study presented of a 57-year-old woman, diagnosed with systemic scleroderma, demonstrating the marked efficacy of the use of metronidazole, an antibiotic in the class of nitroimidazoles, to successfully manage the complication of intestinal pseudo-obstruction, published in the Japanese journal, Nihon RinshŌ Meneki Gakkai Kaishi.

Secondary case study – abstract unavailable but full PDF of study may be purchased at the following link.

A case of pseudoobstruction of the intestine associated with scleroderma dramatically responding to antibiotics. J Gastroenterol. , 41:711


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