Vitamin D poison to Lyme sufferers?

[A Friend]

To those interested in the puzzle about supplementation with high-dose Vitamin D-3, as well as related topics about side effects that some have when taking high-dose vitamin D-3, the following was found tonight. Because of my own year-long side effects (which thankfully are better, but not back to previous normal), I remain very interested in learning “what the heck happened?, and why?” Interesting reading:

http://autoimmunityresearch.org/transcripts/NY_Annals_Waterhouse_Preprint.pdf
Reversing Bacteria-induced Vitamin D
Receptor Dysfunction Is Key
to Autoimmune Disease

Joyce C. Waterhouse,a Thomas H. Perez,b and Paul J. Albert c
a Autoimmunity Research Foundation, Thousand Oaks, California, USA
b US Public Health Service
c Weill Cornell Medical College

Vitamin D research is discussed in light of the hypothesis that the lower average levels of
vitamin D frequently observed in autoimmune disease are not a sign of deficiency.
Instead, it is proposed that the lower levels result from chronic infection with intracellular
bacteria that dysregulate vitamin D metabolism by causing vitamin D receptor (VDR)
dysfunction within phagocytes. The VDR dysfunction causes a decline in innate immune
function that causes susceptibility to additional infections that contribute to disease
progression. Evidence has been accumulating that indicates that a number of autoimmune
diseases can be reversed by gradually restoring VDR function with the VDR agonist
olmesartan and subinhibitory dosages of certain bacteriostatic antibiotics. Diseases
showing favorable responses to treatment so far include systemic lupus erythematosis,
rheumatoid arthritis, scleroderma, sarcoidosis, Sjogren

[Author]

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