Philosophy behind AP rotations

[Luck20]

Hi, just wondering if someone could summarize the philosophy behind using different antibiotics in rotation. I realize different drs do it differently for each protocal and each individual patient, but what is the reasoning?
For instance, some bacteria become resistant? Or some antibiotics combine badly or well? Maybe its easier on the gut to take a break a couple days?

What have you all read or been told?

Originally +Ana May 2018 (now negative Jan 2019), scleroderma or uctd, Morphea (now mostly gone!), Myositis ( better now) Probable Lyme w/coinfections, had Bartonella marks that disappeared,
Mild reflux, mostly gone,mild ild, skin hardening (continued softening and some parts normal again) Impaired liver function, now normal after 1 year and CK, LDH all normal again, 14 mo after starting ap.

Minocin m-f 2x, antibiotic rotation, ldn 4.5, cellcept 3000, probiotics, Monolaurens, Olive leaf extract, fish

[whaleharbor]

I haven’t rotated anything. I don’t know.

Minocycline 100mg every other day with food...lots of food: Zydus brand. Celecoxib 200mg twice per day: Greenstone brand.

[Pinkmoth]

I could be very wrong but the way I like to think about it is like, diff abx will destroy diff bacteria. I think more than one bacteria can induce problems after autoimmunity/inflammation has been triggered. So I feel like rotating gets at other ones who might be problematic as well and knocks them back.
(that’s my uneducated perspective on the matter though)

Autoimmune: ANA positive speckled. Probable MCTD with SD overlap. Hashimoto's. Possible Erlos Danlos. Mold Illness.
Infections: Bartonella, toxoplasmosis, mycoplasma, EBV
Meds: minocycline (Zydus generic) 100mg 1x daily,
Supps: digestive enzymes, Monolaurin, Betaine hydrochloric acid, iron, quercetin, biocidin

[Luck20]

Thanks Pinkmoth, I think your right. I’ve come across explainations of this but I’m interested in other people’s summary and experiences of this. I’m reading about Lyme rotations and possible overlaps with scleroderma.

Originally +Ana May 2018 (now negative Jan 2019), scleroderma or uctd, Morphea (now mostly gone!), Myositis ( better now) Probable Lyme w/coinfections, had Bartonella marks that disappeared,
Mild reflux, mostly gone,mild ild, skin hardening (continued softening and some parts normal again) Impaired liver function, now normal after 1 year and CK, LDH all normal again, 14 mo after starting ap.

Minocin m-f 2x, antibiotic rotation, ldn 4.5, cellcept 3000, probiotics, Monolaurens, Olive leaf extract, fish

[Spiffy1]

With me I do not plan to make any changes as long as I am maintaining how I feel. If it ain’t broke don’t fix it. That is my motto right now. If I were to have a flare then I would have to ask a lot of questions. It is all a guessing game unfortunately. We just have to keep trying.

Flare fall of 2014...muscle aches, joint pains, fatigue, hair loss, rashes, etc.
RA Factor 71 in Jan 2015 down to 25 as of September 2017
DR4/DQ8 HLA...biotoxin illness
IGG food allergy to wheat, egg, and dairy...probably all grains
Vit. C&D, probiotics, milk thistle, turmeric, fish oil, methyl b 12, methyl folate, digestive enzymes, Candisol, Ubiquinol, berberine, chlorella, Moducare, LDN, monolaurin, Triphala, Patriot Greens, Paractin
MTHFR compound heterozygous
Igenex IGM positive Lyme, minoMWF

[Spiffy1]

With me I do not plan to make any changes as long as I am maintaining how I feel. If it ain’t broke don’t fix it. That is my motto right now. If I were to have a flare then I would have to ask a lot of questions. It is all a guessing game unfortunately. We just have to keep trying.

Flare fall of 2014...muscle aches, joint pains, fatigue, hair loss, rashes, etc.
RA Factor 71 in Jan 2015 down to 25 as of September 2017
DR4/DQ8 HLA...biotoxin illness
IGG food allergy to wheat, egg, and dairy...probably all grains
Vit. C&D, probiotics, milk thistle, turmeric, fish oil, methyl b 12, methyl folate, digestive enzymes, Candisol, Ubiquinol, berberine, chlorella, Moducare, LDN, monolaurin, Triphala, Patriot Greens, Paractin
MTHFR compound heterozygous
Igenex IGM positive Lyme, minoMWF

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