Home Forums General Discussion Imuran & Doxycycline drug interaction

This topic contains 4 replies, has 3 voices, and was last updated by  lolly2pops 1 year, 10 months ago.

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  • #457539
    lolly2pops
    Participant

    I am currently on the conventional treatment for systematic scleroderma with lung fibrosis and skin involvement. I need advise on doxycycline and Imuran drug interaction as I am taking both and in addition prednisone 5mg and chloroquine 250mg. Thank you.

    Dx: systemic sclerosis in April 2016 with lung involvement (UiP), raynauds, sausage fingers, and overall swelling, high skin score, general body weakness, fatigue and weight loss . Symptoms started in 2005 and took 10 yrs to get diagnosed. Current meds: 100mg minocycline X2 p/d, milk thistle, turmeryne, mega C 1000 X2 p/d, calcium channel blocker, chloroquine 200mg p/d and probiotics. Tried NAC but this caused stomach pain and discomfort. Other meds used: imuran (oct 2016-dec2017), doxycycline and cellcept

    #457541
    Maz
    Keymaster

    Hi Lollypops,

    Drugs.com has a helpful interactions checker. I plugged in your four medications and appears there are no known interactions, but it’s wise to always crosscheck with your doctor.

    https://www.drugs.com/interactions-check.php?drug_list=593-0,940-0,1936-0,296-139

    Are you taking any supplements?

    Severe, swift onset RA as a result of Lyme disease
    Current Meds: Biaxin (500mg BID), Tetracycline (500mg BID), Tirosint (88mcg), Liothyronine (10 mcg), Compounded Liposomal Artemisinin, LDN (3mg), Topical Progesterone,
    Current Supps: Curcumin, Bovine Colostrum, ALA. NAC, Milk Thistle, Super Liquid Folate/B12/B-Complex, Probiotics, Vit D3
    Supportive Measures: IV Myer's Cocktails, IV Glutathione, FIR Sauna, Gluten-free diet, Gym.

    #457548
    lolly2pops
    Participant

    Hi Maz,

    Thank you for the feedback.

    My Dr assured me that there was no interactions between these two drugs but I came across something disturbing.

    Please checkout these two links: http://www.ehealthme.com/drug-interaction/imuran/doxycycline%20hyclate/
    http://www.ehealthme.com/drug-interaction/doxycycline/azathioprine/

    I’m not taking supplements yet but will soon be adding them to my treatment.

    Dx: systemic sclerosis in April 2016 with lung involvement (UiP), raynauds, sausage fingers, and overall swelling, high skin score, general body weakness, fatigue and weight loss . Symptoms started in 2005 and took 10 yrs to get diagnosed. Current meds: 100mg minocycline X2 p/d, milk thistle, turmeryne, mega C 1000 X2 p/d, calcium channel blocker, chloroquine 200mg p/d and probiotics. Tried NAC but this caused stomach pain and discomfort. Other meds used: imuran (oct 2016-dec2017), doxycycline and cellcept

    #457570
    richie
    Participant

    It seems that I am seeing many folks being advised to use doxycycline as opposed to minocycline –is this productive or effective –I am not so sure !!!!!!!!!!!!!!!!!

    #457575
    lolly2pops
    Participant

    Hi Richie,

    In my case I had to opt for doxycycline as I can not afford minocycline. I am based in South Africa and to get minocycline i would have to chop half of my salary.

    Dx: systemic sclerosis in April 2016 with lung involvement (UiP), raynauds, sausage fingers, and overall swelling, high skin score, general body weakness, fatigue and weight loss . Symptoms started in 2005 and took 10 yrs to get diagnosed. Current meds: 100mg minocycline X2 p/d, milk thistle, turmeryne, mega C 1000 X2 p/d, calcium channel blocker, chloroquine 200mg p/d and probiotics. Tried NAC but this caused stomach pain and discomfort. Other meds used: imuran (oct 2016-dec2017), doxycycline and cellcept

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