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http://www.pbs.org/wgbh/pages/frontline/hunting-the-nightmare-bacteria/
The most intriguing part to me was about the outbreak of KPC ( Klebsiella pneumoniae Carbapenemase http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075864/) at the NIH. I hope I am paraphrasing correctly. My understanding is that they proved it is carried by healthy people with no symptoms and”skips a generation”. They had a small outbreak, thought it was gone, then another bigger batch of patients got very sick. They decided to test every patient there, regardless of symptoms. They made a tree diagram – it showed like 2 patients very sick, then 4 healthy but positive, then 8 very sick. It lived in healthy people’s stomachs. Could this have a connection to why starch avoidance helps AS? It lives off the starch in the people’s stomachs?
More about the episode:
http://www.pbs.org/newshour/rundown/2013/10/frontline-asks-has-the-age-of-antibiotics-come-to-an-end.htmlMom of teen daughter with Poly JIA since age 2. Current med: azithromycin 250 mg MWF.
Reading this made me think of a recent article about SILVER….. Which in turn made me wonder if any of the members here who are on Abx have also used silver simultaneously and with what kind of results ? Is this silver effect on abx new info or has this been known to some and science is just acknowledging? Could this effect result in a greater herx for some on AP? I think I shall dig a little “deeper in the hole” on this one :ugeek: and find out more!
http://stm.sciencemag.org/content/5/190/190ra81.abstractA declining pipeline of clinically useful antibiotics has made it imperative to develop more effective antimicrobial therapies, particularly against difficult-to-treat Gram-negative pathogens. Silver has been used as an antimicrobial since antiquity, yet its mechanism of action remains unclear. We show that silver disrupts multiple bacterial cellular processes, including disulfide bond formation, metabolism, and iron homeostasis. These changes lead to increased production of reactive oxygen species and increased membrane permeability of Gram-negative bacteria that can potentiate the activity of a broad range of antibiotics against Gram-negative bacteria in different metabolic states, as well as restore antibiotic susceptibility to a resistant bacterial strain.
Increased membrane permeability sounds like a good thing …..How about lyme cysts and other biofilms ?
SUZY…
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