I have found many websites about vitamin B12 /must be methylcoalamin/as a potential vitamin of pain killer. B12 reduces homocysteine, an amino acid found at high levels in people with RA. Even moderately elevated homocysteine is associated with an increased risk of fractures. Methotraxate and protein pump inhibitors /drugs that reduce stomach acid/ interfere with B12 absorption.
Here in Australia the “normal” level is 150-700 or with other labs 200-900. So even if you have 150 or 200 they say it is fine. More and more scientists claim that the level below 500 means B12 deficiency. Japan changed their lowest level for 500 two years ago. High doses of vit. B12 have been used to treat some nutritional diseases and diseases like Alzheimer and RA.
Vit. B12 had been usually used as sport nutrition /they know for sure what they are doing!/and used to keep people from getting anemic in past years.
“For fibromyalgia and RA using 1.5-6mg per day,studies noted clinical benefits. 1.5mg per day experience significantly less pain. This is potentially the result of the repair of small nerve fibres close to the skin. Similarly, nerve regeneration is shown to relieve pain in RA, likely due to the stronger nerve fibers being more resistant to irritation from inflamed joints.”
Here is an extract from http://www.naturalhealthadvisory.com:
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RA tried everything: Methotraxate, Arava, Humira. Pneumonia three times. Anemia. Very low iron. Hypothyroidism
AP from April 2014 till August 2015. No luck.
Current medications: Natural thyroid, Mobic, supplements,
vitamins and minerals.
MTHFR heterozygous