Forum Replies Created

Viewing 8 posts - 1 through 8 (of 8 total)
  • Author
  • #461416

    I wholeheartedly agree that quality is of the utmost import, more so than the place of manufacture, although they can be correlated. My husband stopped his Zydus (NDC 68382-316-01) and started the Torrent (NDC 13668-485-01) version this week, so we’ll see if he notices any change. Thanks for staying on top of this.

    Frustrating path to discern where a drug is made and receive conflicting info from the vendor. I called the manufacturer, ZYDUS @ 877.993.8779, 3 times and spoke with 3 different customer service nurses, so if you can’t trust the manufacturer…who can you? Which email address provided the sellersville confirm? I’d like to touch base and see why the company provides incorrect info via the phone route!


    I eagerly await your response. I called again today, mentioned the site and Sellersville info and the story gets cloudier from what I was told. Some ingredients may be sourced from the Sellersville PA plant, but the rest from India WHERE THE PILLS ARE MANUFACTURED. The saga continues. Who knew this was such a tangled web. I’m calling Torrent again now to confirm if their ingredients are all US based. Sigh.


    Interesting. Both my husband and I were told by the ZYDUS customer service nurse (877.993.8779) that the drug is manufactured in India. How do you know it’s a Sellersville PA product?


    Totally agree US versions could be problematic. I did confirm GF Torrent/Ranbaxy/SUN’s 13668485 – 50mg tablets &
    13668482 – 50mg capsules are made by OHM Labs in NJ.

    The deep dive is enlightening:

    – Apotex doesn’t make mino any longer.

    – Caraco now SUN: 57664-0851 (50mg) now made GF in India.

    – Mutual “affiliated” with Sun and does not make Minocycline.

    Guess who is divesting their NJ plants…

    Caraco Pharmaceutical Laboratories, Ltd. is now part of Sun Pharmaceutical Industries Ltd. (February 2011). Sun Pharma has complemented growth with select acquisitions over the last two decades. In 1996, Sun purchased a bulk drug manufacturing plant at Ahmednagar from Knoll Pharmaceuticals and MJ Pharma’s dosage plant at Halol that are both U.S. FDA approved today. In 1997, Sun acquired Tamil Nadu Dadha Pharmaceuticals Limited (TDPL) based in Chennai, mainly for their extensive gynaecology and oncology brands. Also in 1997, Sun Pharma initiated their first foray into the lucrative US market with the acquisition of Caraco Pharmaceuticals, based in Detroit.

    In 1998, Sun acquired a number of respiratory brands from Natco Pharma. Other notable acquisitions include Milmet Labs and Gujarat Lyka Organics (1999), Pradeep Drug Company (2000), Phlox Pharma (2004), a formulation plant at Bryan, Ohio and ICN, Hungary from Valeant Pharma and Able Labs (2005), and Chattem Chemicals (2008). In 2010, the company acquired a large stake in Taro Pharmaceuticals,[13] amongst the largest generic derma companies in the US, with operations across Canada and Israel. The company currently owns ~ 69% stake in Taro, for about $260 million.[14]

    In 2011, Sun Pharma entered into a joint venture with MSD to bring complex or differentiated generics to emerging markets (other than India).

    In 2012, Sun announced acquisitions of two US companies: DUSA Pharmaceuticals,[15] a dermatology device company; and generic pharma company URL Pharma [16] In 2013, the company announced an R&D joint venture for ophthalmology with the research company, Intrexon.[17]

    On 6 April 2014, Sun Pharma announced that it would acquire 100% of Ranbaxy Laboratories Ltd,[18] in an all-stock transaction, valued at $4 billion. Japan’s Daiichi Sankyo held 63.4% stake in Ranbaxy. After this acquisition, Sun Pharma has become the largest pharmaceutical company in India, the largest Indian Pharma company in the US, and the 5th largest generic company worldwide[19]

    In December 2014, the Competition Commission of India approved Sun Pharma’s $3.2 billion bid to buy Ranbaxy Laboratories, but ordered the firms to divest seven products to ensure the deal doesn’t harm competition.[20][21]

    In March 2015, Sun Pharma announced it had agreed to buy GlaxoSmithKline’s opiates business in Australia to strengthen its pain management portfolio.[21]


    I’ve had my eyes opened as part of this search and am shocked by:

    1) How many drugs are made in India (and by company’s fined for unsanitary conditions, etc.) Doc says avoid all India meds if possible. Buy US, Japanese, or Israeli made products exclusively. Could explain why people’s results vary on this forum.

    2) How many drugs contain gluten as a filler, as well as other nasty dyes, etc.

    I’m not sure how much the minute gluten filler would impact my husband’s Celiac Disease, but I’d really prefer to avoid the filler if possible.

    So far, by calling the manufacturer’s I’ve learned the below for 50mg:

    NDC Code Pharma Manufacture location Gluten Free
    0591-5694-60 Actavis India Y
    49884-511 Par NJ N
    68382-0316 Zydus (TEVA) India Y


    Thanks Phil,

    We’re trying to determine where Par manufacturers their product and why it’s labeled non GF. I’ll let you know what I discover. In the meantime, I’m pursuing a compounding pharmacy option. If like spiffy1, we are pay only $100 out of pocket, I consider that a win.

    Re the dosing, based on your experience, would you take 2 50mg once per day on MWF or separate the pills to 1 50mg 2x/day on MWF?

    Re the timing: everything I’ve read mentions IRON avoidance and empty stomach as key. Not really in your experience?

    “Like other tetracyclines, food impairs its absorption. However, the absorption is much less impaired than with other tetracyclines. This is fortunate because some people cannot tolerate Minocin on an empty stomach and have to take it with a meal to avoid GI side effects. If you need to take it with a meal, you will still absorb 85 percent of the medication, whereas tetracycline is only 50 percent absorbed. In June of 1990, a pelletized version of Minocin also became available, which improved absorption when taken with meals.”


    “Over 85 percent of the dose will bind to the iron and pass through your colon unabsorbed. If iron is taken, it should be at least one hour before Minocin, or two hours after.”

    Overall, I’m hoping for remission/cure and no longer needing to dose at all. Fingers crossed and thanks for the information.


    I just called Par to see if their Mino is gluten free and the nurse said no, but I don’t see any gluten in the inactive ingredients. Any idea what would contain gluten?

    Minocycline hydrochloride tablets for oral administration contain minocycline HCl equivalent to 50 mg, 75 mg or 100 mg of minocycline. In addition, 50 mg, 75 mg and 100 mg tablets contain the following inactive ingredients: Microcrystalline Cellulose NF, Lactose Anhydrous NF, Povidone USP, Colloidal Silicon Dioxide NF, Magnesium Stearate NF, and Sodium Starch Glycolate NF. The 50 mg, 75 mg and 100 mg tablets also contain Opadry White which contains: Titanium Dioxide USP, Hypromellose Type 2910 USP, Polyethylene Glycol 400 NF, and Polysorbate 80 NF.


    He’s on sulfasalazine. 1 50mg tablet in the am and 2 50mg tablets in the pm. On the supplement side, he’s taking a compounded mix based on Nutreval deficiency test findings, including pre and probiotics. On the diet side, he’s gluten, dairy, and sugar free with an emphasis on grass finished, pasture raised, organic food heavy on the plant side.

    In the last few days on the increased MINO, he developed bursas on both big toes and his right elbow, along with swollen arches. I’m wondering if this is too much MINO. Doc also recommended he take the nightime dose with dinner. Everything I’ve read to date says take on an empty stomach!

    Speaking of the meds, he has Celiac, so we’re looking for gluten free MINO to boot. The doc doesn’t like any meds not from the US, Japan, or Israel for purity reasons. He disapproves of Ranbaxy specifically. Any recs on effective meds?

    looks like the FDA has concerns or at least did a few years ago based on sanctions and whistleblower’s accounts:

    Thanks for all the help as we navigate towards recovery!

Viewing 8 posts - 1 through 8 (of 8 total)
<< Back To General Discussion