Home Forums General Discussion Vaccine For RA Trialled in Australia

This topic contains 3 replies, has 4 voices, and was last updated by  Linda L 2 years, 6 months ago.

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  • #308722
    enzed
    Participant

    This item was announced on the news in Australia today.
    A Queensland researcher, Professor Ranjeny Thomas has developed a vaccine to reverse RA.
    Apparently it’s been through successful trials.
    Here’s one link to the news item.

    Early clinical trial success for new rheumatoid …
    http://www.uq.edu.au/news/article/2015/06/early-clinical-trial-success-new-rheumatoid-arthritis-treatmentCached
    12 hours ago … UQ Diamantina Institute researcher Professor Ranjeny Thomas said results …

    #374984
    Maz
    Keymaster

    Hi Enzed,

    Thanks for posting this…immunotherapy therapy certainly seems to be a strong focus of research these days for all sorts of diseases, including cancers, and one hopes for other devastating diseases, like scleroderma.

    This one sounds so targeted that it could provide a great way to control RA without all the side-effects of the current immunotherapies, like the injectable (biologics) anti-TNF meds.

    The link was broken above…is this the one you meant to post?

    https://www.uq.edu.au/news/article/2015/06/early-clinical-trial-success-new-rheumatoid-arthritis-treatment

    It’s interesting that they are calling it a “vaccine,” which it is, in effect. My guess is that it won’t be a one-off injection (or series of injections to create resistance as in infectious diseases), but that it will be a drug one would need to inject for life, especially as they are planning to create a drug for mass market use, rather than the individualized early trials they had run, using each patient’s blood products. Nevertheless, it would be pretty amazing if they can produce such a medication that is so targeted that it just blocks the immune response to cyclic citrullinated peptide without shutting down vital elements of the immune response (thus preventing collateral damage and unwanted side-effects). It also seems this vaccine is directed to just those with specific genetic haplotypes and who are anti-CCP positive, but this is one of the most aggressive types of RA and could be an amazing starting point.

    Will be fascinating to watch this research unfold over time and see if it makes it to the market. Thanks for posting! 🙂

    Severe, swift onset RA as a result of Lyme disease
    Current Meds: Biaxin (500mg BID), Tetracycline (500mg BID), Tirosint (88mcg), Liothyronine (10 mcg), Compounded Liposomal Artemisinin, LDN (3mg), Topical Progesterone,
    Current Supps: Curcumin, Bovine Colostrum, ALA. NAC, Milk Thistle, Super Liquid Folate/B12/B-Complex, Probiotics, Vit D3
    Supportive Measures: IV Myer's Cocktails, IV Glutathione, FIR Sauna, Gluten-free diet, Gym.

    #374985
    lynnie_sydney
    Keymaster

    Yes it’s an interesting development. In the TV news bulletin I saw it on, they said the “vaccine” had possible positive implication for MS sufferers also.

    Be well! Lynnie

    Palindromic RA 30 yrs (Chronic Lyme?)
    Mino 2003-2007 100mg MWF - can no longer tolerate mino/doxy
    abx: MWF a.m. Augmentin Duo (1/2 x 875mg) + 250mg Klacid p.m. Cefaclor (1/4 x 375mg) + 250mg Zithromax. Annual Clindy IV's
    Diet: no gluten, dairy, sulphites, low salicylates
    Supps: 600mg N-AC BID, 1000mg Vit C, CoQ10, P5P 40mg, zinc picolinate 60mg, B3 1000mcg, EPO 1000mg, Lithium orotate 20mg, Magnesium Oil equiv 400mg
    Topical bio-identical estradiol + DHEA caps + Progesterone caps

    #374986
    Linda L
    Participant

    It worries me that it is another probably mega-drug which suppresses the immune system. Why don’t they try the opposite?
    Linda L.

    RA tried everything: Methotraxate, Arava, Humira. Pneumonia three times. Anemia Very low iron Hypothyroidism
    AP from April 2014 till August 2015. No luck.
    Current medications: Oroxine, Mobic, Panadol Osteo, supplements incl. milk thistle, NAC, vitamins and minerals.
    MTHFR heterozygous

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