Home Forums General Discussion RHB-104

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  • #371435
    marypart
    Participant

    Richie, What a joy when antibiotics for arthritis and Crohn’s is “mainstream!”

    Here are a couple more links:

    http://www.pipelinereview.com/index.php/2014010653071/Small-Molecules/RedHill-Biopharma-Provides-Update-on-PK-Program-in-Support-of-Ongoing-RHB-104-Phase-III-Crohns-Study.html

    http://www.redhillbio.com/product-pipeline/rhb-104/

    They are recruiting MS patients in Israel for the following clinical trial:

    http://clinicaltrials.gov/show/NCT01717664

    #371436
    Lynne G.SD
    Participant

    Mary/Richie;
    More good news.it looks like just taking an ACE inhibitor for a long time lowers Altzheimer’s by 65%.I was buzy when it came on the news the other night so I only got the tail end where researchers were saying that not one EXPENSIVE med helps and that for pennies a day they sre pretty sure that an ACE will do the trick.This talk was in conjunction with the news that they think they have found a test that everyone should have because Altz starts decades before it is chronic.If test shows positive they want people to get on it right away.They were saying how people who have been on an ACE for years and years have a very low incidence of Altz.Just getting blood flow to the brain is crucial

    #371437
    Woods1977
    Participant

    I agree with one of the previous posts- I’m suprised it’s not generating more buzz… but regardless, I’ll be very interested to see how this pans out in the future. An infectious agent to RA and other auto-immune illness… Hmmm imagine that.

    #371438
    A Friend
    Participant

    @Lynne G./SD wrote:

    Mary/Richie;
    More good news.it looks like just taking an ACE inhibitor for a long time lowers Altzheimer’s by 65%.I was buzy when it came on the news the other night so I only got the tail end where researchers were saying that not one EXPENSIVE med helps and that for pennies a day they sre pretty sure that an ACE will do the trick.This talk was in conjunction with the news that they think they have found a test that everyone should have because Altz starts decades before it is chronic.If test shows positive they want people to get on it right away.They were saying how people who have been on an ACE for years and years have a very low incidence of Altz.Just getting blood flow to the brain is crucial

    Lynne G, if you find more info on this ACE inhibitor, would appreciate your posting a link or links under this topic for us to take closer look at. Thanks for bringing this to our attention.

    AF

    #371439
    Lynne G.SD
    Participant

    Hi Friend;
    This is work being done in Montreal but I expected it would have made the news in other places.Any info I can dig up will be in French

    #371440
    Anonymous
    Participant

    The company RedHill Biopharma Ltd has made one pill, a combination of intracellular, antymycobacterial and anti-inflamatory antibiotics. The same combination RHB-104 is going to treat Crohn’s disease and RA.
    Linda L.

    #371441
    Lynne G.SD
    Participant

    Hey Friend;
    I knew that the Universite de Montreal was working with some American and Dutch researchers and VOILA!!! I found the info in English that was just released
    http://www.healthline.com/health-news/aging-ace-can-help-clear-beta-amyloid-from-the-brain-020314

    #371442
    lemons
    Participant

    @Linda L wrote:

    The company RedHill Biopharma Ltd has made one pill, a combination of intracellular, antymycobacterial and anti-inflamatory antibiotics. The same combination RHB-104 is going to treat Crohn’s disease and RA.
    Linda L.

    RHB-104 (Myconda) , was originally developed by an Australian company for Crohns. Redhill Biopharma has since bought the drug. Its now in trials for not only Crohns and RA, but also for Lupus and MS. This would back up the findings of the now retired microbiologist Dr Wheldon , who has successfully treated and perhaps cured his wife of multiple sclerosis. He believes an infection with chlamydophila pneumonia is behind MS and prescribes for his wife a combination of antibiotics.

    #371443
    A Friend
    Participant

    @Lynne G./SD wrote:

    Hey Friend;
    I knew that the Universite de Montreal was working with some American and Dutch researchers and VOILA!!! I found the info in English that was just released
    http://www.healthline.com/health-news/aging-ace-can-help-clear-beta-amyloid-from-the-brain-020314

    Lynne G….
    Thanks for the link.
    AF

    EDIT:
    PS Lynne G., I just looked over the above link’s health news research into clearing beta amyloid from the brain. It looks like there will not be anything decisive on this for some time.

    It came to mind that so many of us who develop chronic illnesses, did not have an adequate understanding of the “why’s and how-to’s” of keeping the body well-nourished to keep the digestive system from failing. Even when we learn about AP and Dr. Brown’s work, we may not have adequate emphasis on “digestion of nutrients and keeping the gut lining healthy” when we talk about the “right diet” for ourselves.

    Just in case some reading this link have not read/studied these important things we need to know to help our “majestic” bodies recover, they deserve that we should help our bodies by becoming more knowledgeable — or reviewing what we learned some time ago. I put together a few minutes ago in my Word file some links, saving these links so I could find this information more easily for further study. Hope it will be of help to you, too.

    The links below can help us help our minds and bodies NOW. We have a need to understand the important relationships between nutrition, absorption of nutrients from food, restoration of our ability to digest food properly

    #371444
    lemons
    Participant

    How long does a drug in trials take to get approved ? I believe RHB-104 is currently at stage 2 for RA (whatever that means).

    #371445
    Maz
    Keymaster

    @lemons wrote:

    How long does a drug in trials take to get approved ? I believe RHB-104 is currently at stage 2 for RA (whatever that means).

    FDA Trial Stages:

    http://www.nlm.nih.gov/services/ctphases.html

    More in-depth description of the process:

    http://www.fda.gov/drugs/resourcesforyou/consumers/ucm143534.htm

    Article describing odds of getting a new drug to market are 5 in 5000 and may take up to 12 years to get through product testing and trial phases:

    http://www.medicinenet.com/script/main/art.asp?articlekey=9877

    In the case of old abx, this process is likely to be a lot less rigorous as older drugs can receive FDA approval for off-label uses. This was the case with minocycline for RA.

    Whether the trial process is 100% legit or not is a question for debate – for now, the system is “the best we’ve got,” but clearly needs more checks and balances. In it’s October issue, The Economist made a pretty shocking report on drugs used in cancer treatments today that are considered gold standards, but which later independent studies were unable to replicate!

    http://www.economist.com/news/leaders/21588069-scientific-research-has-changed-world-now-it-needs-change-itself-how-science-goes-wrong

    “Last year researchers at one biotech firm, Amgen, found they could reproduce just six of 53

    #371446
    lemons
    Participant

    I noticed that RHB-104 is mentioned now on several mainstream arthritis websites. I also saw a post regarding Crohns and AP, so I thought I would bring this thread up again. I have read that Myconda the original name of the drug, has already been used for a while to treat Crohns .

    #371447
    Jan Lucinda1
    Participant

    RedHill Biopharma is in Tel-Aviv, Israel. I’m glad there are researchers continuing to do research to treat RA.

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