Home Forums General Discussion new abstract – myco infected cells and neutrophils

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    Suzanne
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    http://www.ncbi.nlm.nih.gov/pubmed/23997221

    “J Immunol. 2013 Aug 30. [Epub ahead of print]
    Mycobacteria-Infected Dendritic Cells Attract Neutrophils That Produce IL-10 and Specifically Shut Down Th17 CD4 T Cells through Their IL-10 Receptor.”

    “Abstract
    Neutrophils participate in the control of mycobacterial infection both by directly eliminating bacilli and by interacting with macrophages and dendritic cells (DCs). Despite host defenses, slow-growing mycobacteria can persist in the host for decades, mostly inside macrophages and DCs, and eventually destroy tissues after exacerbated inflammation. IL-17A-driven neutrophil recruitment may participate in this process. We report that mouse bone marrow-derived DCs infected with live Mycobacterium bovis Bacillus Calmette-Gu

    Mom of teen daughter with Poly JIA since age 2. Current med: azithromycin 250 mg MWF.

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