Home Forums General Discussion Discolouration of my eye pupils, face and neck areas

This topic contains 19 replies, has 5 voices, and was last updated by  Lynne G.SD 1 year, 8 months ago.

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  • #457624
    cookie
    Participant

    I’m concerned as my pupils are starting to discolour. They appear to be grayish. My face and neck are also discoloured and I have small black cysts on my cheeks and forehead. I have had laser surgery on my face twice but it hasn’t helped to remove anything. Is there a product or vitamin that might help reduce the discolouration. I am on minocycline 2 100 mg pills 3 times a week. I take many supplements as well. I have had RA 13 years. Any advice would be appreciated as I don’t know how to rectify this situation. Thank you!

    Diagnosed with RA in 2004. Taking minocycline M W F 100mg 2xday. Taking B vitamins, fish oil, probiotics, vit E, calcium, vit D, DHEA, zinc, kaprex, magnesium taurine, curcumin, msm, GLA, vitamin C. Using topical ointments for pain such as Liv Relief, Croyderm and Voltaren. Eating gluten free bread, lactose free milk, lean meat such as chicken and fruits and veggies. Exercising 5 times a week. My side effects of mino are hyperpigmentation of my face/neck and darkening of my gums and whites of eyes.

    #457625
    lynnie_sydney
    Participant

    Hy cookie
    You might want to take a look at this very recent thread:

    HEY MAZ…blue spots

    Be well! Lynnie

    Palindromic RA 30 yrs (Chronic Lyme?)
    Mino 2003-2008 100mg MWF - can no longer tolerate any tetracyclines
    abx from Sep 2018 MWF - a.m. Augmentin Duo 440mg + 150mg Biaxsig (roxithromycin). p.m. Cefaclor (375mg) + Klacid 125mg. Annual Clindy IV's
    Diet: no gluten, dairy, sulphites, low salicylates
    Supps: 600mg N-AC BID, 1000mg Vit C, CoQ10, P5P 40mg, zinc picolinate 60mg, B3 1000mcg, EPO 1000mg, Lithium orotate 20mg, Magnesium Oil equiv 400mg. Topical bio-identical estradiol, DHEA +

    #457628
    Lynne G.SD
    Participant

    Hi Cookie;
    I finally found a sure fix thanks to my prof.I got bored and decided to go back to Uni. and take a couple interesting(to me) courses.One is called La Bio Chemie des Supplements and it is amazing.Naturally with a bunch of girls in the class and much to the chagrin of the guys the topic turned to cosmetics one day.When I mentione C serum he asked me what rock I was living under.The he got on the topic of B vits.WOW,they are amazing.He the gave us free reign to tear into the cosmetic industry.What fun we had for a couple days.There are loads of doubleblind peer reviewed articles all in French or German but I found some English equivalents if you want me to send them.Check out Inositol ,it’s making my hair grow like stink and Niacinamide for skin discolouration.With SD we always get that muddy looking SD tan and even though I have been in remission for 15 years the coluur never left on the calves or chest,the grubby looking elbows and knees from years of gardening are just about gone in less than a month.Even my sun/age spots are fading dramatically.Get a large bottle of body cream such as Aveno or Lubriderm and empty 2 capsules of niacinamide,shake really well and use daily.Then take 1 capsule daily,it usually comes in 500mg and is dirt cheap.One can take up to 300mg a day before it becomes toxic so there are no worries about 500mg

    #457754
    cookie
    Participant

    Yes please if you would kindly send me the English studies thanks so much Lynne.

    Diagnosed with RA in 2004. Taking minocycline M W F 100mg 2xday. Taking B vitamins, fish oil, probiotics, vit E, calcium, vit D, DHEA, zinc, kaprex, magnesium taurine, curcumin, msm, GLA, vitamin C. Using topical ointments for pain such as Liv Relief, Croyderm and Voltaren. Eating gluten free bread, lactose free milk, lean meat such as chicken and fruits and veggies. Exercising 5 times a week. My side effects of mino are hyperpigmentation of my face/neck and darkening of my gums and whites of eyes.

    #457755
    cookie
    Participant

    Hi how much inositol is safe ? My hair is terribly thin and I would love to thicken it. Thanks so much

    Diagnosed with RA in 2004. Taking minocycline M W F 100mg 2xday. Taking B vitamins, fish oil, probiotics, vit E, calcium, vit D, DHEA, zinc, kaprex, magnesium taurine, curcumin, msm, GLA, vitamin C. Using topical ointments for pain such as Liv Relief, Croyderm and Voltaren. Eating gluten free bread, lactose free milk, lean meat such as chicken and fruits and veggies. Exercising 5 times a week. My side effects of mino are hyperpigmentation of my face/neck and darkening of my gums and whites of eyes.

    #457756
    cookie
    Participant

    Hi thanks for the threads. I wish I could solve my pupils graying. Would taking vitamin C in high doses say 3000 mg help eliminate the build up of iron from the mino in my body. Really concerned about the discolouration of my pupils. Thanks

    Diagnosed with RA in 2004. Taking minocycline M W F 100mg 2xday. Taking B vitamins, fish oil, probiotics, vit E, calcium, vit D, DHEA, zinc, kaprex, magnesium taurine, curcumin, msm, GLA, vitamin C. Using topical ointments for pain such as Liv Relief, Croyderm and Voltaren. Eating gluten free bread, lactose free milk, lean meat such as chicken and fruits and veggies. Exercising 5 times a week. My side effects of mino are hyperpigmentation of my face/neck and darkening of my gums and whites of eyes.

    #457805
    PhilC
    Participant

    Hi Cookie,

    Do you normally take any vitamin C? I take 500 mg, 2 to 3 times a day.

    I have some black discoloration on my feet and on my left ankle. I also have some bluish-grey discoloration on my gums. I am not concerned about it (yet) because it is just a cosmetic issue at this point, and most people never see it anyway. However, if I had the discoloration on my face, or it was affecting my eyes, I would be concerned.

    Have you considered switching to a different antibiotic, like doxycycline?

    Phil

    "Unthinking respect for authority is the greatest enemy of truth."
    - Albert Einstein

    #457809
    cookie
    Participant

    Hi Phil;
    How does vitamin C help? I’ll try it because it doesn’t stay in our system. The side effects of minocycline unfortunately is discolouration, where it does discolour is hit or miss I would think. It’s a concern but I guess I have to live with it. I tried doxycycline but it didn’t help with the severe body aches. Thank you for your help.
    Cookie

    Diagnosed with RA in 2004. Taking minocycline M W F 100mg 2xday. Taking B vitamins, fish oil, probiotics, vit E, calcium, vit D, DHEA, zinc, kaprex, magnesium taurine, curcumin, msm, GLA, vitamin C. Using topical ointments for pain such as Liv Relief, Croyderm and Voltaren. Eating gluten free bread, lactose free milk, lean meat such as chicken and fruits and veggies. Exercising 5 times a week. My side effects of mino are hyperpigmentation of my face/neck and darkening of my gums and whites of eyes.

    #457812
    Maz
    Keymaster

    Hi Cookie,

    This study explains why and how vitamin C helps prevent minocycline-induced hyperpigmentation:

    https://www.ncbi.nlm.nih.gov/pubmed/9893512

    The tetracyclines are very chelatuve and bind to minerals in the body, such as iron, and in studies I’ve seen where biopsies were conducted on these colored patches, there is a higher concentration of iron deposited there. Vitamin C is known to help metabolize iron in the body, which is why docs will recommend drinking down an iron tablet with orange juice or something with a high vitamin C content to help with absorption.

    I had my thyroid removed last year due to a toxic multinodular goiter and I asked the surgeon if it was blue/gray/black when she took it out and she said it was a normal color. I’d been on tetras for 9 years at that point, but have always taken vitamin c (ascorbic acid powder) and do bi-weekly IV Myer’s cocktails and use a number of other antioxidative supps ( NAC, ALA, curcumin, and glutathione IV pushes). Maybe that is why I’ve never had any big issues, though I do still get gray/brownish patchy freckles on my forarms and chest in summer, they fade during the winter.

    Hope this helps.

    Severe, swift onset RA as a result of Lyme disease
    Current Meds: Biaxin (500mg BID), Tetracycline (500mg BID), Tirosint (88mcg), Liothyronine (10 mcg), Compounded Liposomal Artemisinin, LDN (3mg), Topical Progesterone,
    Current Supps: Curcumin, Bovine Colostrum, ALA. NAC, Milk Thistle, Super Liquid Folate/B12/B-Complex, Probiotics, Vit D3
    Supportive Measures: IV Myer's Cocktails, IV Glutathione, FIR Sauna, Gluten-free diet, Gym.

    #457837
    PhilC
    Participant

    Hi Cookie,

    How does vitamin C help? I’ll try it because it doesn’t stay in our system.

    Since Maz already answered you, I’ll answer from a different angle. Vitamin C is important even if you don’t have discolouration because it is an anti-oxidant, and because the body needs it in order to produce collagen.

    I tried doxycycline but it didn’t help with the severe body aches.

    How much doxycycline were you taking?

    Phil

    "Unthinking respect for authority is the greatest enemy of truth."
    - Albert Einstein

    #457846
    cookie
    Participant

    Hi: I was taking the doxycycline for 6 months to replace the minocycline on M-W-F twice a day. My body aches came back with a vengeance and my right wrist became swollen to match my left ☹️️. I went back on minocycline and can function most days. My RA is in both wrists which has virtually eliminated my weight lifting, push ups etc. which saddens me tremendously. But I am fortunate that it’s only in my wrists so far after 12 years.

    Diagnosed with RA in 2004. Taking minocycline M W F 100mg 2xday. Taking B vitamins, fish oil, probiotics, vit E, calcium, vit D, DHEA, zinc, kaprex, magnesium taurine, curcumin, msm, GLA, vitamin C. Using topical ointments for pain such as Liv Relief, Croyderm and Voltaren. Eating gluten free bread, lactose free milk, lean meat such as chicken and fruits and veggies. Exercising 5 times a week. My side effects of mino are hyperpigmentation of my face/neck and darkening of my gums and whites of eyes.

    #457859
    PhilC
    Participant

    Hi Cookie,

    Since doxycycline is weaker than minocycline, it would have been better if you had been taking it every day. Even so, it might not have helped if the bacteria are resistant to doxy.

    What country are you in? Depending on where you are, you may have other options.

    Phil

    "Unthinking respect for authority is the greatest enemy of truth."
    - Albert Einstein

    #457862
    cookie
    Participant

    Hi Phil; I live in Toronto, Ontario, Canada. I see Dr J who is a great complementary physician. I have started to take 2 1000 Mg of Vitamin C a day now and hope it may help eliminate the discolouration or at least halt its progression.

    Diagnosed with RA in 2004. Taking minocycline M W F 100mg 2xday. Taking B vitamins, fish oil, probiotics, vit E, calcium, vit D, DHEA, zinc, kaprex, magnesium taurine, curcumin, msm, GLA, vitamin C. Using topical ointments for pain such as Liv Relief, Croyderm and Voltaren. Eating gluten free bread, lactose free milk, lean meat such as chicken and fruits and veggies. Exercising 5 times a week. My side effects of mino are hyperpigmentation of my face/neck and darkening of my gums and whites of eyes.

    #458095
    cookie
    Participant

    Maz: I purchased the buffered vitamin C. It is 1000mg in strength. It also contains a small amount of calcium 125 mg and 100mg of quercetin. I need your advice as to when I should take the tablets?? Do you take yours with the minocycline. I really want to eliminate the black discolouration from the whites of my eyes. Thank you very much!
    Cookie

    Diagnosed with RA in 2004. Taking minocycline M W F 100mg 2xday. Taking B vitamins, fish oil, probiotics, vit E, calcium, vit D, DHEA, zinc, kaprex, magnesium taurine, curcumin, msm, GLA, vitamin C. Using topical ointments for pain such as Liv Relief, Croyderm and Voltaren. Eating gluten free bread, lactose free milk, lean meat such as chicken and fruits and veggies. Exercising 5 times a week. My side effects of mino are hyperpigmentation of my face/neck and darkening of my gums and whites of eyes.

    #458102
    Lynne G.SD
    Participant

    Cookie;
    You have to remember that it will take quite a while to get rid of the colouring as you have to wait until the bottom layer of the skin becomes the top layer,do you understand?The dark colour penetrates the entire tissue and as new tissue forms it is always the bottom layer.Are you taking any niacinamide as it inhibits melanin which causes the dark spots.I take 1500mg a day with great effect.

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