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February 22, 2010 at 9:19 am #303513PhilCParticipant
A fairly recent alert about diclofenac was added to the top of this page:
http://www.nlm.nih.gov/medlineplus/druginfo/meds/a689002.htmlPhil
"Unthinking respect for authority is the greatest enemy of truth."
- Albert EinsteinFebruary 22, 2010 at 1:01 pm #341680lynnie_sydneyParticipantThank you very much for this Phil. Lynnie
Be well! Lynnie
Palindromic RA 30 yrs (Chronic Lyme?)
Mino 2003-2008 100mg MWF - can no longer tolerate any tetracyclines
rotating abx protocol now. From Sep 2018 MWF - a.m. Augmentin Duo 440mg + 150mg Biaxsig (roxithromycin). p.m. Cefaclor (375mg) + Klacid 125mg + LDN 3mg + Annual Clindy IV's
Diet: no gluten, dairy, sulphites, low salicylates
Supps: 600mg N-AC BID, 1000mg Vit C, P5P 40mg, zinc picolinate 60mg, Lithium orotate 20mg, Magnesium Oil, Bio-identical hormones (DHEA + Prog + Estrog)February 24, 2010 at 8:02 am #341681superperroRAParticipantI've taken voltaren (50mg suppositories 3 times a day) for more than a year. My doctor does blood tests of my liver and kidney function every 2 months and so far everything is fine. With RA, you have to pick your poisons. If you look at the list of possible side-effects for methotraxate, you'll faint.
February 24, 2010 at 5:17 pm #341682RandyParticipantI'm sorry, but I don't understand what is new here. Yes, NSAIDS have had a warning about stomach ulcers and the need to maintain observation of kidney and liver values. As far as I can tell, there is absolutely nothing new here. Please correct me if I am wrong.
Diffuse SD since Apr '07
AP since Feb '08
100mg Mino twice daily
Stopped Clindamycin IVs Aug 2019
"No one should profit over someone else's illness"February 25, 2010 at 1:31 am #341683lynnie_sydneyParticipantRandy – this is new information on some severe adverse hepatic effects that have been monitored and have caused Novartis to revise its warning re this drug and the liver. Lynnie
Posted 12/04/2009] Endo, Novartis and FDA notified healthcare professionals of revisions to the Hepatic Effects section of the prescribing information to add new warnings and precautions about the potential for elevation in liver function tests during treatment with all products containing diclofenac sodium.
In postmarketing reports, cases of drug-induced hepatotoxicity have been reported in the first month but can occur at any time during treatment with diclofenac. Postmarketing surveillance has reported cases of severe hepatic reactions, including liver necrosis, jaundice, fulminant hepatitis with and without jaundice, and liver failure. Some of these reported cases resulted in fatalities or liver transplantation.Be well! Lynnie
Palindromic RA 30 yrs (Chronic Lyme?)
Mino 2003-2008 100mg MWF - can no longer tolerate any tetracyclines
rotating abx protocol now. From Sep 2018 MWF - a.m. Augmentin Duo 440mg + 150mg Biaxsig (roxithromycin). p.m. Cefaclor (375mg) + Klacid 125mg + LDN 3mg + Annual Clindy IV's
Diet: no gluten, dairy, sulphites, low salicylates
Supps: 600mg N-AC BID, 1000mg Vit C, P5P 40mg, zinc picolinate 60mg, Lithium orotate 20mg, Magnesium Oil, Bio-identical hormones (DHEA + Prog + Estrog)February 25, 2010 at 2:27 am #341684RandyParticipantThanks for the clarification!
Diffuse SD since Apr '07
AP since Feb '08
100mg Mino twice daily
Stopped Clindamycin IVs Aug 2019
"No one should profit over someone else's illness" -
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