Home Forums General Discussion Cutting Edge Supplement for Pain & Inflammation

This topic contains 26 replies, has 11 voices, and was last updated by  cl10s 1 week ago.

Viewing 15 posts - 1 through 15 (of 27 total)
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  • #460861
    Red Lizzy
    Participant

    I live on the internet due to my business, so I come across the newest supplements on a regular basis, whether they are good or not remains to be seen, but this one in particular is the best I have ever found if pain & inflammation is your problem, it was mine.

    First I have to say I was in a auto accident 20+ years ago that caused some nasty disc issues, had surgery that helped for a few years,but eventually I moved on to meds, from tylenol to tramadol to oxycodone, we all know how that goes. Even oxycodone wasn’t doing what it used to and I did not want to keep increasing the dose, so I kept my eye out for something to help. The best of the drugs was Celebrex, but it is only matter of time before the cardiovascular issues get you. The best of the natural stuff was curcumin, boswellia and Devil’s claw. Even these can wreck your gut if taken long enough, so I kept looking.

    A few months back I came across something different, a substance that is hardly known here, but well known in Europe called Palmitoylethanolamide, also known as PEA for short. This is a totally natural lipotrophic substance found in nature and produced by our bodies during times of injuries to help heal tissues. Only problem is when an issue becomes chronic, the production of this in the body cannot keep up with the needs, so that is where supplementation comes in. A few companies manufacture it, but really only one in the Netherlands has a pharmaceutical grade product. Basically you go through a loading phase for a month or two then on to a maintenance dose. A big plus for this is that there have been a few hundred clinical trials over the years done on it by reputable scientists, including Nobel Laureates, so it has been validated as safe, side effect free and effective. Works on all kinds of pain,including neuropathy and they even found it is useful in MS, ALS and autoimmune issues.

    Considering all this I just had to try it, so I went through the dosing routine and now, as long as I take my maintenance dose, I barely use any meds for pain/neuropathy,sometimes going days without even one pill. I will add some links to some good info. I think this is a great addition to AP. This can help you eliminate prednisone, celebrex and even worse drugs. I hope this can be useful for some here. Both Amazon and eBay have these for sale. If you have any questions, please do not hesistate to ask, I have done a lot or research on this and used it succcessfully, so should be able to give you an accurate response. Best of Luck! Liz

    https://palmitoylethanolamide4pain.com/
    https://www.palmitoylethanolamide.com/
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500919/
    https://www.ncbi.nlm.nih.gov/pmc/?term=palmitoylethanolamide

    #460862
    Linda L
    Participant

    Liz, it is interesting. How long have you been taking it and how much?

    RA tried everything: Methotraxate, Arava, Humira. Pneumonia three times. Anemia Very low iron Hypothyroidism
    AP from April 2014 till August 2015. No luck.
    Current medications: Oroxine, Mobic, Panadol Osteo, supplements incl. milk thistle, NAC, vitamins and minerals.
    MTHFR heterozygous

    #460863
    Red Lizzy
    Participant

    Liz, it is interesting. How long have you been taking it and how much?

    Hi Linda,

    Happy to answer any questions you have. First I have to say I was an extreme case, I had been on the heavy meds since 2011, each year came an increase in dosage due to more tolerance for opiods and also opiods create a condition called hyperanalgesia, which means then basically lower your pain theshold so things that normally would not cause you pain end up doing so, they basically make it almost impossible for you to make a clean break!

    I started using PEA in April of this year, initially at the recommends 3 caps daily, in a week I noticed a slight benefit but not enough for my needs,so I began to increase, one cap at a time until I was taking 3 in the morning and 3 at night, that made a big difference. This dose is well within the guidelines the manufacturer recommends. After being on it for about a month I began to lower the dose, currently my maintenance is 3 caps, 2+1, which allows me to maintain the benefits. I occassionaly use a tramadol,maybe twice a week, which is significantly less potent than what I was on, and pretty easy to get a script for. I highly doubt you are in my situation.

    The recommended dosing to start off is 2+1 for 50 days, then lower to your maintenance, usually 1+1 daily, which seems to work for most people. This is the best thing I have ever done for myself and feel so much better because of it. In a way I believe it may have been one of the reasons I ended up getting sick due to immune supression caused by opiods.

    The brand I use is Ergomax Opti-Pea, made in the Netherlands, which is the highest purity brand out there, over 99%. If you decide to try it stay away from other brands, they most likely are Chinese products packaged here and next to worthless and are not much cheaper. If you need more info just let me know. Thank you. Liz

    #460864
    Linda L
    Participant

    Thank you Liz.

    RA tried everything: Methotraxate, Arava, Humira. Pneumonia three times. Anemia Very low iron Hypothyroidism
    AP from April 2014 till August 2015. No luck.
    Current medications: Oroxine, Mobic, Panadol Osteo, supplements incl. milk thistle, NAC, vitamins and minerals.
    MTHFR heterozygous

    #460868
    lynnie_sydney
    Keymaster

    Linda – some information on PEA and links to further info by this Australian compounding pharmacy – who do make it up for patients: National Custom Compounding

    Be well! Lynnie

    Palindromic RA 30 yrs (Chronic Lyme?)
    Mino 2003-2007 100mg MWF - can no longer tolerate mino/doxy
    abx: MWF a.m. Augmentin Duo (1/2 x 875mg) + 250mg Klacid p.m. Cefaclor (1/4 x 375mg) + 250mg Zithromax. Annual Clindy IV's
    Diet: no gluten, dairy, sulphites, low salicylates
    Supps: 600mg N-AC BID, 1000mg Vit C, CoQ10, P5P 40mg, zinc picolinate 60mg, B3 1000mcg, EPO 1000mg, Lithium orotate 20mg, Magnesium Oil equiv 400mg
    Topical bio-identical estradiol + DHEA caps + Progesterone caps

    #460871
    Dawn
    Participant

    RedLizzy, I PM’d you regarding this – let me know if you do not receive my message.

    Dawn

    DawnF

    #460879
    Linda L
    Participant

    Thank you Lynnie.

    RA tried everything: Methotraxate, Arava, Humira. Pneumonia three times. Anemia Very low iron Hypothyroidism
    AP from April 2014 till August 2015. No luck.
    Current medications: Oroxine, Mobic, Panadol Osteo, supplements incl. milk thistle, NAC, vitamins and minerals.
    MTHFR heterozygous

    #460880
    Red Lizzy
    Participant

    RedLizzy, I PM’d you regarding this – let me know if you do not receive my message.

    Dawn

    RedLizzy, I PM’d you regarding this – let me know if you do not receive my message.

    Dawn

    Sorry, not always logged in so am not aware of the message. JUst checked and replied to your PM, if you need more info just PM again, I will check from now on, just in case. Liz

    #460951
    vinny
    Participant

    PEA is something I had never heard of but is worth an evaluation. I started using it on Oct 30 along with my wife. I started with the American version supplied by Nootropics Depot, but have also ordered the European version from Amazon. I think it is worth trying to keep this thread active so more people will be aware of it. I will report my results as time goes by. As you can see from my byline I am treating the symptoms of psoriatic arthritis successfully with Minocycline. I have no joint discomfort, just a few connective tissue “hot spots.” The only serious issue I have is problems with a restrictive stiff neck. I respond very well to Prednisone and just finished a Prednisone Dose Pac, starting with 60mg the first day and decreasing the dosage by 10mg each day for 6 days. That got my neck mobility back and I will see if the PEA maintains that flexibility. My wife has spinal issues as well as Sarcoidosis. She can’t use NSAID’s and relies on Hydrocodone for pain management.

    Psoriatic Arthritis: 250mg Azithromycin M,W,F; 100mg Minocycline TABLET daily; twice daily 400mg Pentoxifylline;100mcg Levotyroxine; 4mg LDN at arise. Have been using some level of Minocycline since 2008

    #460969
    Red Lizzy
    Participant

    Vinny,

    I think you will be very happy with the results you and your wife obtain from PEA. I brought a bottle to my Pain Management doctor when I first started using it so he would know what I was doing. He remarked that I looked better than he has seen me in a while, probably due to the decrease in inflammation or something. He took down the name so he could look into it and after researching it he purchased some for himself!. I just saw him yesterday and he was raving about how he felt, so that says a lot! I hope to hear your updates, I am sure they will be good also. Getting off the hardcore drugs has really been a relief for my body. Good Luck!

    Liz

    #460972
    Spiffy1
    Participant

    Does anyone know if the PEA supplement is still made from egg yolks? 1 am considering this supplement but allergic to eggs.

    Flare fall of 2014...muscle aches, joint pains, fatigue, hair loss, rashes, etc.
    RA Factor 71 in Jan 2015 down to 28 as of September 2016
    DR4/DQ8 HLA...biotoxin illness
    IGG food allergy to wheat, egg, and dairy...probably all grains
    Vit. C&D, probiotics, milk thistle, turmeric, fish oil, methyl b 12, methyl folate, digestive enzymes, Candisol, Ubiquinol, berberine, chlorella, Moducare, LDN, monolaurin, Triphala, Patriot Greens, Paractin
    MTHFR compound heterozygous
    Igenex IGM positive Lyme, minoMWF

    #460974
    Red Lizzy
    Participant

    Does anyone know if the PEA supplement is still made from egg yolks? 1 am considering this supplement but allergic to eggs.

    First only consider the products made in the Netherlands, that are pure PEA only, Opti-Pea. Next email them and ask the source. I have found them very good at responding all my emails within 24 hours. Never consider any bulk powder that lists China, guaranteed contaminated and worthless. All the top brands use the product Opti-Pea made in the Netherlands, not sure if egg based or not (I hope not for your sake, so you can use it)

    https://www.optipea.com/

    #460975
    Spiffy1
    Participant

    Thank you!!! Will do!!!

    Flare fall of 2014...muscle aches, joint pains, fatigue, hair loss, rashes, etc.
    RA Factor 71 in Jan 2015 down to 28 as of September 2016
    DR4/DQ8 HLA...biotoxin illness
    IGG food allergy to wheat, egg, and dairy...probably all grains
    Vit. C&D, probiotics, milk thistle, turmeric, fish oil, methyl b 12, methyl folate, digestive enzymes, Candisol, Ubiquinol, berberine, chlorella, Moducare, LDN, monolaurin, Triphala, Patriot Greens, Paractin
    MTHFR compound heterozygous
    Igenex IGM positive Lyme, minoMWF

    #460994
    pattyrod
    Participant

    Liz,

    I would like to try the Ergomax Opti-Pea. Amazon is out of stock. Do you know where else I can purchase it from (besides The Netherlands)?

    Thanks,
    Patty

    #460996
    Linda L
    Participant

    Lizzy,
    You are writing about caps. How much is a cap? 200 or 400mg?

    RA tried everything: Methotraxate, Arava, Humira. Pneumonia three times. Anemia Very low iron Hypothyroidism
    AP from April 2014 till August 2015. No luck.
    Current medications: Oroxine, Mobic, Panadol Osteo, supplements incl. milk thistle, NAC, vitamins and minerals.
    MTHFR heterozygous

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