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hello, all.
My name is Jeff, and I'm new here to the forums. It's my understanding that the diagnosis for Rheumatoid Arthritis (and probably other Rheumatic diseases) was done by looking at various blood test levels (RH factor, sed rate, etc.) and the doctor determining the disease. Now, I've been told, that a new test, AntiCCP, is a sure-fire way to tell if you have RA. Have others had this test as well?, and is it true that if the levels are high, that basically the other blood tests don't matter or are not needed? Over the past several years, I've had blood tests done that, according to doc, have not necessarily indicated RA; UNTIL my levels on the anitCCP test were high, so diagnosis was easy now.
Also, how common is mis-diagnosis of RA, in light of this new test?
Thank you.
Jeff
See
http://en.wikipedia.org/wiki/Sensitivity_%28tests%29
There are two types of errors in a test: false positives (FP) and false negatives (FN). Tests with high sensitivity yield low FN. Tests with high specificity yield low FP.
Now look at
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1754666
“The sensitivity and specificity of anti-CCP reactivity for the diagnosis of rheumatoid arthritis (RA) were 66.0% and 90.4%, respectively.”
So, for anti-ccp, the probability of FP is small (10%)
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